![]() The May 1999 edition of Burns I think had a comparison article. I also remember an article from Journal of Clinical Derm but I can't seem to find it right now. These are the two I had in my database, I'd have to do a more intensive search. Topical Bactroban (mupirocin): efficacy in treating burn wounds infected with PubMed PMID: 8150836.Ģ: Strock LL, Lee MM, Rutan RL, Desai MH, Robson MC, Herndon DN, Heggers JP. Collagenase ointment and polymyxin B sulfate/bacitracinspray versus silver sulfadiazine cream in partial-thickness burns: a pilot study. It's expensive also when Bacitracin cost spare change and does just as well1: Soroff HS, Sasvary DH. It's not really new research it's just that the Silvidine isn't supported in what is there. Most people don't clean the Silvidine off well enough when they do dressing changes. What topical do you all use in the acute phase of burns? What is best practice?ĭefinitely Bacitracin it pt is going to be taking care of at home. Plus, the benefit of SSD is that it cools down the burning sensations. I can see infection setting in if the silvadene burn dressing isn't changed BID, but not otherwise. It would be sacrilege to forgo the SSD at my burn center. I have seen SSD heal many many burns plus it is antimicrobial. I was shocked to hear that and I can't find this research, nor have I heard of it. In the treatment of burn wounds involving extensive areas of the body, the serum sulfa concentrations may approach adult therapeutic levels (8 mg to 12 mg). Avoid contact of SILVADENE Cream 1 (silver sulfadiazine) with the eye. It takes dedicated BID changes and SSD can macerate intact skin) and so he prefers to use just bacitracin and gauze. SILVADENE Cream 1 (silver sulfadiazine) is for topical use only. I started work at a new wound clinic that hardly sees many burns, but whenever we get one, the doctor says that there is "new research" that says silvadene causes terrible infections, is ineffective and it's hard/messy for patients to do at home ( I agree with the hard/messy part. I have read that the burn center at Mass General has long used silver nitrate soaks instead of SSD. ![]() ![]() They keep in silvadene (SSD) for long term if they aren't getting grafted, then downgrade to xeroform and then perhaps plain bacitracin. At my burn center, we place new burns in silvadene dressings BID (or we have a protocol for silver nitrate soaks if I'm on-call, the burn isn't life-threatening and the attending isn't coming in until the morning) for the few days before they are grafted.
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